Lily’s Second Chance

Senior Mixed Breed dogs in Missouri

Senior Mixed Breed dogs for adoption in Missouri

Meet 35 adoptable senior Mixed Breed dogs (age 7+) in Missouri. Each one is from a shelter or rescue and ready for a calm, loving home.

Older Mixed Breeds in Missouri are often passed over for puppies, yet they're usually house-trained, settled in temperament, and ready to bond right away — and because they're fully grown, you already know their size and personality. Adopting a senior Mixed Breed in Missouri means welcoming a calm, grateful companion who can settle in from day one. Adopters browsing senior Mixed Breeds in Missouri are often also looking at Pit Bull Terrier and Labrador Retriever listed here. Senior Mixed Breeds are also listed in 37 other states if you can travel for the right match.

Last updated November 9, 2026 at 1:47 AM EST. Listings refresh throughout the day. Always confirm a dog’s availability with the shelter or rescue before making plans.

All senior Mixed Breed dogsAll senior dogs in Missouri

Available senior Mixed Breed dogs in Missouri

35 senior Mixed Breed dogs available in Missouri.

Senior confirmed
Photo of Elephant, adoptable senior Mixed Breed (Large) in St. Louis, Missouri

Elephant

Mixed Breed (Large) • Female • 9 years

Dog Reactive · Spayed · No Kids · Stranger Danger · Behavioral Issues - Must Work with Stray Rescue Training · Special Needs · The One Love Club

Stray Rescue of St. Louis • St. Louis, MO

View profileView Adoption Page ↗ (opens in a new tab)
10+ years
Photo of Rolex, adoptable senior Mixed Breed (Large) in St. Louis, Missouri

Rolex

Mixed Breed (Large) • Male • 10 years

Neutered · Stranger Danger · The One Love Club · No Cats · No Kids · Single Dog Home · Behavioral Issues - Must Work with Stray Rescue Training · Spec…

Stray Rescue of St. Louis • St. Louis, MO

View profileView Adoption Page ↗ (opens in a new tab)
Senior confirmed
Photo of Ralph, adoptable senior Mixed Breed (Medium) in Pineville, Missouri

Ralph

Mixed Breed (Medium) • Male • 9 years

Good with Dogs · Good with Kids · Housetrained · Knows basic commands · Walks on leash · Respectful of personal space · Good with Cats

I'm Your Huckleberry Rescue • Pineville, MO

View profileView Adoption Page ↗ (opens in a new tab)

Senior Mixed Breed dogs in other states

Florida96Texas91New York39Maryland29Indiana28Tennessee26California22Delaware17Virginia13Georgia11Illinois11North Carolina11

Other senior dogs in Missouri by breed

Pit Bull Terrier21Labrador Retriever14German Shepherd11Shih Tzu4Border Collie3Great Pyrenees3Shepherd3Siberian Husky3Yorkshire Terrier Yorkie3Mastiff2Poodle2Staffordshire Terrier2

Senior dogs in Missouri by city

St Louis43Kansas City21St Peters21Maryland10Lee's Summit7Savannah6St. Charles5Boonville4Bolivar3Bridgeton2Fenton2O'fallon2

Adopting a senior Mixed Breed in Missouri — FAQ

What counts as a senior dog?

Most shelters and vets consider a dog "senior" around age 7, though large breeds often age sooner and small breeds a little later. Every dog listed here is 7 years or older.

How do I adopt a senior Mixed Breed in Missouri?

Open any dog's profile to see the shelter or rescue caring for them in Missouri, then use the adoption link or contact details to apply directly with that organization. Lily's Second Chance simply gathers senior Mixed Breeds in one place so they're easier to find.

Are there always senior Mixed Breed dogs available in Missouri?

Availability changes often as dogs are adopted and new ones are listed. If you don't see a senior Mixed Breed in Missouri right now, check back soon or browse nearby states — new dogs are added regularly.

Can I adopt a senior Mixed Breed from Missouri if I live elsewhere?

Often, yes. Many rescues and shelters in Missouri arrange or help coordinate transport for the right adopter, while others prefer a local meet-and-greet first. Open a dog's profile and ask the organization directly how their out-of-area adoption process works.

Guides to help you decide

Getting started

Why Adopt a Senior Dog? 7 Reasons Older Dogs Make Wonderful Companions

Senior dogs are often calm, house-trained, and overlooked at shelters. Here are seven honest reasons an older dog may be the best companion you ever bring home.

6 min readUnderstanding age

How Old Is a "Senior" Dog? Senior Age by Breed and Size

A dog is not "old" at the same age across the board — size and breed change everything. Here is how to tell when a dog becomes a senior, and what it means for care.

5 min readCare & health

Caring for a Senior Dog: Health, Diet, and Everyday Comfort

How to keep an older dog healthy and comfortable — vet care, senior-appropriate diet, joint and dental health, exercise, and simple home adjustments that make a big difference.

8 min read

Know a senior Mixed Breed in Missouri who needs a home?

Shelters and rescues can list adoptable senior dogs for free.

Submit a senior dogBrowse resources